欧盟评估停滞棒杆菌KCCM 80235生产的肌苷酸二钠作为所有动物饲料添加剂的安全性和有效性

2022年3月7日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就停滞棒杆菌（Corynebacterium stationis）KCCM 80235生产的肌苷酸二钠disodium 5’-inosinate）作为所有动物饲料添加剂的安全性和有效性发表科学意见。

经过评估，专家小组无法就添加剂对目标物种、消费者、使用者和环境的安全性做出结论。专家小组认为该添加剂能有效地改善饲料和饮用水的风味。

部分原文报道如下：

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of disodium 5’-inosinate (IMP) produced by fermentation using Corynebacterium stationis KCCM 80235 as a sensory additive (flavouring compound) in feed and water for drinking for all animal species. The production strain is genetically modified, and it is resistant to streptomycin. No viable cells were detected in the final product. However, uncertainties remained on the genetic basis of the streptomycin resistance and on the possible presence of recombinant DNA from the production strain in the final product. Therefore, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) could not conclude on the safety of the additive for the target species, consumers, users and the environment. Moreover, the FEEDAP Panel reiterated its previous concerns on the safety of the use of IMP in water for drinking due to hygienic reasons. The Panel concluded that the additive is efficacious to contribute to the flavour of feed and water for drinking.